IMN

Biblio. IMN

Référence en vue solo

Lavenus, S., Trichet, V., Le Chevalier, S., Hoornaert, A., Louarn, G. & Layrolle, P. (2012) Cell differentiation and osseointegration influenced by nanoscale anodized titanium surfaces. Nanomedicine, 7 967–980. 
Added by: Laurent Cournède (2016-03-10 21:28:39)
Type de référence: Article
DOI: 10.2217/NNM.11.181
Numéro d'identification (ISBN etc.): 1743-5889
Clé BibTeX: Lavenus2012
Voir tous les détails bibliographiques
Catégories: PMN
Mots-clés: anodized titanium, behavior, bone bonding strength, bone response, bone-to-implant contact, iii collagen, implants, in-vitro, matrix protein comp, mechanical strain, Mesenchymal stem cells, mesenchymal stem-cells, nanostructured surfaces, Osteoblasts, osteogenic differentiation, tio2 nanotubes
Créateurs: Hoornaert, Lavenus, Layrolle, Le Chevalier, Louarn, Trichet
Collection: Nanomedicine
Consultations : 6/421
Indice de consultation : 2%
Indice de popularité : 0.5%
Résumé     
Aims: We aimed to study the interactions between human mesenchymal stem cells and the bone integration of nanostructured titanium implants. Materials \& methods: Nanopores of 20, 30 and 50 nm were prepared by anodization of titanium at 5, 10 and 20 V in a mixture of fluorhydric and acetic acid. Ti 30 and 50 nanostructures promoted early osteoblastic gene differentiation of the human mesenchymal stem cells without osteogenic supplements. The osseointegration of nanostructured and control titanium implants was compared by implantation in rat tibias for 1 and 3 weeks. Results: The nanostructures significantly accelerated bone apposition and bone bonding strength in vivo in correlation with in vitro results. Conclusion: These findings demonstrate that specific nanostructures controlled the differentiation of cells and, thus, the integration of implants in tissues. These nanoporous titanium surfaces may be of considerable interest for dental and orthopedic implants.
Added by: Laurent Cournède  
wikindx 4.2.2 ©2014 | Références totales : 2592 | Requêtes métadonnées : 68 | Exécution de script : 0.11635 secs | Style : Harvard | Bibliographie : Bibliographie WIKINDX globale