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Buchtova, N., D'Orlando, A., Judeinstein, P., Chauvet, O., Weiss, P. & Le Bideau, J. (2018) Water dynamics in silanized hydroxypropyl methylcellulose based hydrogels designed for tissue engineering. Carbohydrate Polymers, 202 404–408.
Added by: Richard Baschera (2018-12-19 09:41:04) Last edited by: Richard Baschera (2018-12-19 09:44:28) |
| Type de référence: Article DOI: 10.1016/j.carbpol.2018.08.143 Clé BibTeX: Buchtova2018 Voir tous les détails bibliographiques  |
Catégories: PMN Créateurs: Buchtova, Chauvet, D'Orlando, Judeinstein, Le Bideau, Weiss Collection: Carbohydrate Polymers |
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Silanized hydroxypropyl methylcellulose based hydrogels were developed for cartilage and intervertebral disc tissue engineering. Herein, study of dynamics of confined water showed two different populations, identified as hydration and bulk-like water. The diffusion coefficient showed that bulk-like water diffuses over distances similar to 10 mu m without being affected by the hydrogel matrix. Addition of silica nanofibers leads to improved mechanical properties and enhanced diffusion coefficient. Good diffusion within hydrogels is essential for the application.
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